Mutt and Jeff
From The Arthur Conan Doyle Encyclopedia

Mutt and Jeff is a long-running and widely popular American newspaper comic strip created by cartoonist Bud Fisher in 1907 about "two mismatched tinhorns". It is commonly regarded as the first daily comic strip.
The series includes at least 6 strips related to Arthur Conan Doyle's Sherlock Holmes published in various American newspapers from 1918 and 1946.
In 1926, an animated movie starring Mutt & Jeff was released : Slick Sleuths (Modern Film Sales Corporation).
Comic strips
1918
1921
- 14.06.1921 : At Deduction Sherlock Holmes had Nothing on Jeff
1930
- 15.03.1930 : Mutt a la Sherlock Holmes
1934
- 04.06.1934 : Jeff Must Have Been Reading Sherlock Holmes
1944
1946
Video
Slick Sleuths (1926)